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Target
D(2) dopamine receptor
Ligand
BDBM50023840
Substrate
n/a
Meas. Tech.
ChEBML_61437
IC50
>1000±n/a nM
Citation
 Monkovic, I; Willner, D; Adam, MA; Brown, M; Crenshaw, RR; Fuller, CE; Juby, PF; Luke, GM; Matiskella, JA; Montzka, TA Substituted benzamides. 1. Potential nondopaminergic antagonists of chemotherapy-induced nausea and emesis. J Med Chem 31:1548-58 (1988) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2_RAT | Dopamine D2 receptor | Dopamine2-like | Drd2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
50931.60
Organism:
Rattus norvegicus (rat)
Description:
P61169
Residue:
444
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC
  
Inhibitor
Name:
BDBM50023840
Synonyms:
3-Amino-2-chloro-11-ethyl-6,7,10,11,12,13,14,15-octahydro-9H-5,8-dioxa-11,15-diaza-benzocyclotetradecen-16-one | CHEMBL41530
Type:
Small organic molecule
Emp. Form.:
C16H24ClN3O3
Mol. Mass.:
341.833
SMILES:
CCN1CCCNC(=O)c2cc(Cl)c(N)cc2OCCOCC1
Structure:
Search PDB for entries with ligand similarity: