Reaction Details Report a problem with these data
Target
Muscarinic receptor M1
Ligand
BDBM50018226
Substrate
n/a
Meas. Tech.
ChEBML_138126
Ki
3400±n/a nM
Citation
 Leader, H; Smejkal, RM; Payne, CS; Padilla, FN; Doctor, BP; Gordon, RK; Chiang, PK Binary antidotes for organophosphate poisoning: aprophen analogues that are both antimuscarinics and carbamates. J Med Chem 32:1522-8 (1989) [PubMed]  Article 
Target
Name:
Muscarinic receptor M1
Synonyms:
Muscarinic acetylcholine receptor M1
Type:
PROTEIN
Mol. Mass.:
15022.43
Organism:
Bos taurus
Description:
ChEMBL_140161
Residue:
139
Sequence:
ETENRARELAALQGSETPGKGGGSSSSSERSQPGAEGSPETPPGRCCRCCRTPRLLQAYSWKEEEEEDEGSMESLTSSEGEEPGSEVVIKMPMVDPEAQAPAKQPPRSSPNTVKRPTRKGRERAGKGQKPRGKEQLAKR
  
Inhibitor
Name:
BDBM50018226
Synonyms:
2-(4-Dimethylcarbamoyloxy-phenyl)-2-(4-hydroxy-phenyl)-propionic acid 2-diethylamino-ethyl ester | CHEMBL288482
Type:
Small organic molecule
Emp. Form.:
C24H32N2O5
Mol. Mass.:
428.5213
SMILES:
CCN(CC)CCOC(=O)C(C)(c1ccc(O)cc1)c1ccc(OC(=O)N(C)C)cc1
Structure:
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