Reaction Details Report a problem with these data
Target
Alpha-mannosidase 2C1
Ligand
BDBM50016703
Substrate
n/a
Meas. Tech.
ChEBML_105324
IC50
100000±n/a nM
Citation
 Winkler, DA; Holan, G Design of potential anti-HIV agents. 1. Mannosidase inhibitors. J Med Chem 32:2084-9 (1989) [PubMed]  Article 
Target
Name:
Alpha-mannosidase 2C1
Synonyms:
MA2C1_RAT | Man2c1
Type:
PROTEIN
Mol. Mass.:
115965.84
Organism:
Rattus norvegicus
Description:
ChEMBL_32499
Residue:
1040
Sequence:
MAAAPFLKHWRTTFERVEKFVSPIYFTDCNLRGRLFGDSCPVTLSSFLTPERLPYEKAVQQNFSPAQVGDSFGPTWWTCWFRVELVIPEVWVGKEVHLCWESDGESLVWRDGEPVQGLTKEGEKTSYVLSERLHAADPRSLTLYVEVACNGLLGAGKGSMIAAPDPEKMFQLSQAKLAVFHRDVHNLLVDLELLLGVAKGLGEDNQRSFQALYTANQMVNICDPAQPETYPAAEALASKFFGQRGGESQHTIHATGHCHIDTAWLWPFKETVRKCARSWSTAVKLMERNTEFTFACSQAQQLEWVKNQYPGLYAQLQEFACRGQFVPVGGTWVEMDGNLPSGEAMVRQFLQGQNFFLQEFGKMCSEFWLPDTFGYSAQLPQIMQGCGIKRFLTQKLSWNLVNSFPHHTFFWEGLDGSQVLVHFPPGDSYGMQGSVEEVLKTVTNNRDKGRTNHSGFLFGFGDGGGGPTQTMLDRLKRLGNTDGQPRVQLSSPGQLFTALERDSGQLCTWVGELFLELHNGTYTTHAQLKKGNRECEQILHDVELLSSLALARSAQFLYPAVQLQRLWRLLLLNQFHDVVTGSCIQLVAEDAMNYYEDIRSHGNTLLSAAAAALCAGEPGPKGLRHYQHTALEAHRSVGTTQGLVGLTRLALVTVPSIGYAPAPTPTSLQPLLPQQPVFVMQETDGSVTLDNGIIRVRLDPTGCLTSLVLVASGREAIAEGALGNQFVLFDDVPLYWDAWDVMDYHLETRKPVRGQAGTLAVGAEGGLRGSAWFLLQISPNSRLSQEVVLDVGCPYVRFHTEVHWHETHKFLKVEFPARVRSPQATYEIQFGHLQEADPQQHSWDWARYEVWAHRWIDLSECDFGLALLNNCKYGTSVRGNVLSLSLLRAPKAPDVTADMGRHEFTYALMPHKGSFQEAGVIQAAYNLNFPLLALPAPGPAPDTTWSAFSVSSPAVVLETIKQAEKSHQHRTLVLRLYEAHGSHVDCWLHTSLPVQEATLCDLLEQRDPTGHLSLQDNRLKLTFSPFQVRSLLLVLQPPAN
  
Inhibitor
Name:
BDBM50016703
Synonyms:
2-Hydroxymethyl-pyrrolidine-3,4-diol | BDBM50031485 | CHEMBL80254 | Imino-D-Arabinitol
Type:
Small organic molecule
Emp. Form.:
C5H11NO3
Mol. Mass.:
133.1457
SMILES:
OC[C@H]1NC[C@@H](O)[C@@H]1O |r|
Structure:
Search PDB for entries with ligand similarity: