Reaction Details Report a problem with these data
Target
Glutamate dehydrogenase 1, mitochondrial
Ligand
BDBM50368057
Substrate
n/a
Meas. Tech.
ChEBML_71835
Ki
>10000000±n/a nM
Citation
 Goldstein, BM; Bell, JE; Marquez, VE Dehydrogenase binding by tiazofurin anabolites. J Med Chem 33:1123-7 (1990) [PubMed]  Article 
Target
Name:
Glutamate dehydrogenase 1, mitochondrial
Synonyms:
DHE3_BOVIN | GLUD | GLUD1 | Glutamate dehydrogenase
Type:
PROTEIN
Mol. Mass.:
61518.81
Organism:
Bos taurus
Description:
ChEMBL_71835
Residue:
558
Sequence:
MYRYLGEALLLSRAGPAALGSASADSAALLGWARGQPAAAPQPGLVPPARRHYSEAAADREDDPNFFKMVEGFFDRGASIVEDKLVEDLKTRETEEQKRNRVRSILRIIKPCNHVLSLSFPIRRDDGSWEVIEGYRAQHSQHRTPCKGGIRYSTDVSVDEVKALASLMTYKCAVVDVPFGGAKAGVKINPKNYTDNELEKITRRFTMELAKKGFIGPGVDVPAPDMSTGEREMSWIADTYASTIGHYDINAHACVTGKPISQGGIHGRISATGRGVFHGIENFINEASYMSILGMTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCITVGESDGSIWNPDGIDPKELEDFKLQHGTILGFPKAKIYEGSILEVDCDILIPAASEKQLTKSNAPRVKAKIIAEGANGPTTPEADKIFLERNIMVIPDLYLNAGGVTVSYFEWLNNLNHVSYGRLTFKYERDSNYHLLMSVQESLERKFGKHGGTIPIVPTAEFQDRISGASEKDIVHSGLAYTMERSARQIMRTAMKYNLGLDLRTAAYVNAIEKVFRVYNEAGVTFT
  
Inhibitor
Name:
BDBM50368057
Synonyms:
NSC-286193 | TIAZOFURINE
Type:
Small organic molecule
Emp. Form.:
C9H12N2O5S
Mol. Mass.:
260.267
SMILES:
NC(=O)c1csc(n1)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O |r|
Structure:
Search PDB for entries with ligand similarity: