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Target
Glutamate dehydrogenase 1, mitochondrial
Ligand
BDBM50421763
Substrate
n/a
Meas. Tech.
ChEBML_71835
Ki
4500±n/a nM
Citation
 Goldstein, BM; Bell, JE; Marquez, VE Dehydrogenase binding by tiazofurin anabolites. J Med Chem 33:1123-7 (1990) [PubMed]  Article 
Target
Name:
Glutamate dehydrogenase 1, mitochondrial
Synonyms:
DHE3_BOVIN | GLUD | GLUD1 | Glutamate dehydrogenase
Type:
PROTEIN
Mol. Mass.:
61518.81
Organism:
Bos taurus
Description:
ChEMBL_71835
Residue:
558
Sequence:
MYRYLGEALLLSRAGPAALGSASADSAALLGWARGQPAAAPQPGLVPPARRHYSEAAADREDDPNFFKMVEGFFDRGASIVEDKLVEDLKTRETEEQKRNRVRSILRIIKPCNHVLSLSFPIRRDDGSWEVIEGYRAQHSQHRTPCKGGIRYSTDVSVDEVKALASLMTYKCAVVDVPFGGAKAGVKINPKNYTDNELEKITRRFTMELAKKGFIGPGVDVPAPDMSTGEREMSWIADTYASTIGHYDINAHACVTGKPISQGGIHGRISATGRGVFHGIENFINEASYMSILGMTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCITVGESDGSIWNPDGIDPKELEDFKLQHGTILGFPKAKIYEGSILEVDCDILIPAASEKQLTKSNAPRVKAKIIAEGANGPTTPEADKIFLERNIMVIPDLYLNAGGVTVSYFEWLNNLNHVSYGRLTFKYERDSNYHLLMSVQESLERKFGKHGGTIPIVPTAEFQDRISGASEKDIVHSGLAYTMERSARQIMRTAMKYNLGLDLRTAAYVNAIEKVFRVYNEAGVTFT
  
Inhibitor
Name:
BDBM50421763
Synonyms:
CHEMBL2364562
Type:
Small organic molecule
Emp. Form.:
C19H25N7O14P2S
Mol. Mass.:
669.453
SMILES:
NC(=O)c1csc(n1)[C@H]1O[C@@H](COP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2cnc3c(N)ncnc23)[C@H](O)[C@@H]1O |r|
Structure:
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