Reaction Details Report a problem with these data
Target
D(1A) dopamine receptor
Ligand
BDBM50004820
Substrate
n/a
Meas. Tech.
ChEBML_58969
Ki
7±n/a nM
Citation
 Pettersson, I; Liljefors, T; Bøgesø, K Conformational analysis and structure-activity relationships of selective dopamine D-1 receptor agonists and antagonists of the benzazepine series. J Med Chem 33:2197-204 (1990) [PubMed]  Article 
Target
Name:
D(1A) dopamine receptor
Synonyms:
DA D1 receptor | DOPAMINE D1 | DRD1 | DRD1_HUMAN | Dopamine D1 receptor | Dopamine D1 receptor (D1R) | Dopamine D1A
Type:
Enzyme
Mol. Mass.:
49303.43
Organism:
Homo sapiens (Human)
Description:
P21728
Residue:
446
Sequence:
MRTLNTSAMDGTGLVVERDFSVRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTSPSDGNATSLAETIDNCDSSLSRTYAISSSVISFYIPVAIMIVTYTRIYRIAQKQIRRIAALERAAVHAKNCQTTTGNGKPVECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCILPFCGSGETQPFCIDSNTFDVFVWFGWANSSLNPIIYAFNADFRKAFSTLLGCYRLCPATNNAIETVSINNNGAAMFSSHHEPRGSISKECNLVYLIPHAVGSSEDLKKEEAAGIARPLEKLSPALSVILDYDTDVSLEKIQPITQNGQHPT
  
Inhibitor
Name:
BDBM50004820
Synonyms:
3-Chloro-7-methyl-5,6,7,7a,8,12b-hexahydro-7-aza-dibenzo[a,h]azulen-2-ol | CHEMBL307790
Type:
Small organic molecule
Emp. Form.:
C18H18ClNO
Mol. Mass.:
299.795
SMILES:
CN1CCc2cc(Cl)c(O)cc2[C@@H]2[C@@H]1Cc1ccccc21
Structure:
Search PDB for entries with ligand similarity: