Reaction Details Report a problem with these data
Target
Mu-type opioid receptor
Ligand
BDBM50009127
Substrate
n/a
Meas. Tech.
ChEBML_145153
Ki
189±n/a nM
Citation
 Portoghese, PS; Garzon-Aburbeh, A; Nagase, H; Lin, CE; Takemori, AE Role of the spacer in conferring kappa opioid receptor selectivity to bivalent ligands related to norbinaltorphimine. J Med Chem 34:1292-6 (1991) [PubMed]  Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOR-1 | Mu opioid receptor | Mu-type opioid receptor (Mu) | OPIATE Mu | OPRM1 | OPRM_CAVPO
Type:
Enzyme Catalytic Domain
Mol. Mass.:
11165.58
Organism:
GUINEA PIG
Description:
P97266
Residue:
98
Sequence:
YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI
  
Inhibitor
Name:
BDBM50009127
Synonyms:
bis(4-cyclopropylmethyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,14-tetraene-10,17-diol)thiphene
Type:
Small organic molecule
Emp. Form.:
C40H42N2O6S
Mol. Mass.:
678.836
SMILES:
Oc1ccc2CC3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1sc2[C@@H]4Oc6c7c(CC8N(CC9CC9)CC[C@@]47[C@@]8(O)Cc2c1C[C@@]35O)ccc6O |TLB:3:4:43:7.13.12,45:26:37:29.35.34,17:18:43:7.13.12,24:25:37:29.35.34|
Structure:
Search PDB for entries with ligand similarity: