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Target
Sigma non-opioid intracellular receptor 1
Ligand
BDBM50006973
Substrate
n/a
Meas. Tech.
ChEMBL_201291 (CHEMBL805781)
IC50
>10000±n/a nM
Citation
 Glennon, RA; Ismaiel, AM; Smith, JD; Yousif, M; el-Ashmawy, M; Herndon, JL; Fischer, JB; Howie, KJ; Server, AC Binding of substituted and conformationally restricted derivatives of N-(3-phenyl-n-propyl)-1-phenyl-2-aminopropane at sigma-receptors. J Med Chem 34:1855-9 (1991) [PubMed]  Article 
Target
Name:
Sigma non-opioid intracellular receptor 1
Synonyms:
Opioid receptor | Oprs1 | SGMR1_RAT | Sigma | Sigma non-opioid intracellular receptor 1 | Sigma opioid receptor | Sigma-1 | Sigmar1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
25266.54
Organism:
RAT
Description:
Q9R0C9
Residue:
223
Sequence:
MPWAVGRRWAWITLFLTIVAVLIQAVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSRLIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSHGHSGRYWAEISDTIISGTFHQWREGTTKSEVYYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPSTLAFALSDTIFSTQDFLTLFYTLRAYARGLRLELTTYLFGQDP
  
Inhibitor
Name:
BDBM50006973
Synonyms:
CHEMBL298758 | [2-(3,4-Dichloro-phenyl)-1-methyl-ethyl]-(3-phenyl-propyl)-amine
Type:
Small organic molecule
Emp. Form.:
C18H21Cl2N
Mol. Mass.:
322.272
SMILES:
CC(Cc1ccc(Cl)c(Cl)c1)NCCCc1ccccc1
Structure:
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