Reaction Details Report a problem with these data
Target
Adenosine deaminase
Ligand
BDBM50368280
Substrate
n/a
Meas. Tech.
ChEBML_30795
Ki
6900±n/a nM
Citation
 Cristalli, G; Vittori, S; Eleuteri, A; Grifantini, M; Volpini, R; Lupidi, G; Capolongo, L; Pesenti, E Purine and 1-deazapurine ribonucleosides and deoxyribonucleosides: synthesis and biological activity. J Med Chem 34:2226-30 (1991) [PubMed]  Article 
Target
Name:
Adenosine deaminase
Synonyms:
ADA | ADA_BOVIN | Adenosine aminohydrolase
Type:
Enzyme
Mol. Mass.:
40910.44
Organism:
Bos taurus (bovine)
Description:
n/a
Residue:
363
Sequence:
MAQTPAFNKPKVELHVHLDGAIKPETILYYGRKRGIALPADTPEELQNIIGMDKPLSLPEFLAKFDYYMPAIAGCREAVKRIAYEFVEMKAKDGVVYVEVRYSPHLLANSKVEPIPWNQAEGDLTPDEVVSLVNQGLQEGERDFGVKVRSILCCMRHQPSWSSEVVELCKKYREQTVVAIDLAGDETIEGSSLFPGHVKAYAEAVKSGVHRTVHAGEVGSANVVKEAVDTLKTERLGHGYHTLEDATLYNRLRQENMHFEVCPWSSYLTGAWKPDTEHPVVRFKNDQVNYSLNTDDPLIFKSTLDTDYQMTKNEMGFTEEEFKRLNINAAKSSFLPEDEKKELLDLLYKAYGMPSPASAEQCL
  
Inhibitor
Name:
BDBM50368280
Synonyms:
CHEMBL612157
Type:
Small organic molecule
Emp. Form.:
C11H13ClN4O5
Mol. Mass.:
316.698
SMILES:
OC[C@H]1OC([C@H](O)[C@@H]1O)n1cnc2c(NO)cc(Cl)nc12 |r|
Structure:
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