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Target
Beta-1 adrenergic receptor
Ligand
BDBM50002138
Substrate
n/a
Meas. Tech.
ChEBML_39323
Ki
400±n/a nM
Citation
 Meurer, LC; Tolman, RL; Chapin, EW; Saperstein, R; Vicario, PP; Zrada, MM; MacCoss, M Synthesis and hypoglycemic activity of substituted 8-(1-piperazinyl)imidazo[1,2-a]pyrazines. J Med Chem 35:3845-57 (1992) [PubMed]  Article 
Target
Name:
Beta-1 adrenergic receptor
Synonyms:
ADRB1 | Adrenergic receptor | adrenergic Beta1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
50540.48
Organism:
GUINEA PIG
Description:
adrenergic Beta1 ADRB1 GUINEA PIG::B0FL73
Residue:
467
Sequence:
MGAGVLALGASEPCNLSSTAPLPDGAATAARLLVPASPPASLLPPTSEGSEPLSPQWTAGMGLLMVLIVLLIVAGNVLVIVAIAKTPRLQTLTNLFIMSLASADLVMGLLVVPFGATIVVWGRWEYGSFFCELWTSVDVLCVTASIETLCVIALDRYLAITSPFRYQSLLTRARARVLVCTVWAISALVSFLPILMHWWRAEGDEARRCYNDPKCCDFVTNRAYAIASSVVSFYVPLCIMAFVYLRVFREAQKQVKKIDSCERRFLGGPGRPPSPVPSPTPGSPRAATDPLANGRTSKRRPSRLVALREQKALKTLGIIMGVFTLCWLPFFLANVVKAFHRDLVPDRLFVFFNWLGYANSAFNPIIYCRSPDFRKAFQRLLCCARRAARRRHTAHGGRPRASGCLARSGPPPSPGAASDEDEDAVGAAPPARLLEPWAGCNGGAATADSDWSLDEPGRAGFASESKV
  
Inhibitor
Name:
BDBM50002138
Synonyms:
3,5-Dimethyl-8-piperazin-1-yl-imidazo[1,2-a]pyrazine; 2M.hydrochloride | CHEMBL543653
Type:
Small organic molecule
Emp. Form.:
C12H17N5
Mol. Mass.:
231.2969
SMILES:
Cc1cnc2c(ncc(C)n12)N1CCNCC1
Structure:
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