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Target
Beta-1 adrenergic receptor
Ligand
BDBM50000502
Substrate
n/a
Meas. Tech.
ChEMBL_37542 (CHEMBL647624)
Ki
15000±n/a nM
Citation
 Macchia, B; Balsamo, A; Breschi, MC; Lapucci, A; Lucacchini, A; Macchia, F; Manera, C; Martinelli, A; Martini, C; Martinotti, E Conformational effects on the activity of drugs. 13. A revision of previously proposed models for the activation of alpha- and beta-adrenergic receptors. J Med Chem 35:1009-18 (1992) [PubMed]  Article 
Target
Name:
Beta-1 adrenergic receptor
Synonyms:
ADRB1R, B1AR | ADRB1_RAT | Adrb1 | Adrb1r | Adrenergic receptor beta | Beta-1 adrenoceptor | Beta-1 adrenoreceptor | adrenergic Beta1 | adrenergic Beta1,2
Type:
Protein
Mol. Mass.:
50486.84
Organism:
Rattus norvegicus (Rat)
Description:
P18090
Residue:
466
Sequence:
MGAGALALGASEPCNLSSAAPLPDGAATAARLLVLASPPASLLPPASEGSAPLSQQWTAGMGLLLALIVLLIVVGNVLVIVAIAKTPRLQTLTNLFIMSLASADLVMGLLVVPFGATIVVWGRWEYGSFFCELWTSVDVLCVTASIETLCVIALDRYLAITLPFRYQSLLTRARARALVCTVWAISALVSFLPILMHWWRAESDEARRCYNDPKCCDFVTNRAYAIASSVVSFYVPLCIMAFVYLRVFREAQKQVKKIDSCERRFLTGPPRPPSPAPSPSPGPPRPADSLANGRSSKRRPSRLVALREQKALKTLGIIMGVFTLCWLPFFLANVVKAFHRDLVPDRLFVFFNWLGYANSAFNPIIYCRSPDFRKAFQRLLCCARRAACRRRAAHGDRPRASGCLARAGPPPSPGAPSDDDDDDAGATPPARLLEPWAGCNGGTTTVDSDSSLDEPGRQGFSSESKV
  
Inhibitor
Name:
BDBM50000502
Synonyms:
4-Morpholin-2-yl-benzene-1,2-diol | CHEMBL7681
Type:
Small organic molecule
Emp. Form.:
C10H13NO3
Mol. Mass.:
195.2151
SMILES:
Oc1ccc(cc1O)C1CNCCO1
Structure:
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