Reaction Details Report a problem with these data
Target
Cholecystokinin receptor type A
Ligand
BDBM50046114
Substrate
n/a
Meas. Tech.
ChEBML_49724
Ki
1400±n/a nM
Citation
 Corringer, PJ; Weng, JH; Ducos, B; Durieux, C; Boudeau, P; Bohme, A; Roques, BP CCK-B agonist or antagonist activities of structurally hindered and peptidase-resistant Boc-CCK4 derivatives. J Med Chem 36:166-72 (1993) [PubMed]  Article 
Target
Name:
Cholecystokinin receptor type A
Synonyms:
CCK-A receptor | CCK-AR | CCK1-R | CCKAR | CCKAR_CAVPO | Cholecystokinin A receptor | Cholecystokinin receptor type A | Cholecystokinin-1 receptor
Type:
n/a
Mol. Mass.:
48229.77
Organism:
Cavia porcellus
Description:
n/a
Residue:
430
Sequence:
MDVVDSLFVNGSNITSACELGFENETLFCLDRPRPSKEWQPAVQILLYSLIFLLSVLGNTLVITVLIRNKRMRTVTNIFLLSLAVSDLMLCLFCMPFNLIPSLLKDFIFGSAVCKTTTYFMGTSVSVSTFNLVAISLERYGAICKPLQSRVWQTKSHALKVIAATWCLSFTIMTPYPIYSNLVPFTKNNNQTGNMCRFLLPNDVMQQTWHTFLLLILFLIPGIVMMVAYGLISLELYQGIKFDAIQKKSAKERKTSTGSSGPMEDSDGCYLQKSRHPRKLELRQLSPSSSGSNRINRIRSSSSTANLMAKKRVIRMLIVIVVLFFLCWMPIFSANAWRAYDTVSAERHLSGTPISFILLLSYTSSCVNPIIYCFMNKRFRLGFMATFPCCPNPGTPGVRGEMGEEEEGRTTGASLSRYSYSHMSTSAPPP
  
Inhibitor
Name:
BDBM50046114
Synonyms:
3-(2-Amino-3-naphthalen-1-yl-propionylamino)-N-{[1-tert-butoxycarbonyl-2-(1H-indol-3-yl)-ethylcarbamoyl]-cyclohexyl-methyl}-succinamic acid | CHEMBL3351058
Type:
Small organic molecule
Emp. Form.:
C40H49N5O7
Mol. Mass.:
711.8464
SMILES:
CC(C)(C)OC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](N)Cc1cccc2ccccc12)C1CCCCC1
Structure:
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