Reaction Details Report a problem with these data
Target
Gag-Pol polyprotein [489-587]
Ligand
BDBM50422001
Substrate
n/a
Meas. Tech.
ChEBML_157867
Ki
10.0±n/a nM
Citation
 Chong, KT; Ruwart, MJ; Hinshaw, RR; Wilkinson, KF; Rush, BD; Yancey, MF; Strohbach, JW; Thaisrivongs, S Peptidomimetic HIV protease inhibitors: phosphate prodrugs with improved biological activities. J Med Chem 36:2575-7 (1993) [PubMed]  Article 
Target
Name:
Gag-Pol polyprotein [489-587]
Synonyms:
Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol
Type:
Enzyme Subunit
Mol. Mass.:
10781.16
Organism:
Human immunodeficiency virus type 1
Description:
P04585[489-587]
Residue:
99
Sequence:
PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
  
Inhibitor
Name:
BDBM50422001
Synonyms:
CHEMBL2304002
Type:
Small organic molecule
Emp. Form.:
C42H59N5O7
Mol. Mass.:
745.9472
SMILES:
CC(C)[C@H](C[C@H](O)[C@H](CC1CCCCC1)NC(=O)[C@@H](NC(=O)COc1cccc2ccccc12)C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N(C)c1ccccn1
Structure:
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