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Target
Plasminogen
Ligand
BDBM50046896
Substrate
n/a
Meas. Tech.
ChEMBL_155050 (CHEMBL764369)
IC50
1100±n/a nM
Citation
 McConnell, RM; York, JL; Frizzell, D; Ezell, C Inhibition studies of some serine and thiol proteinases by new leupeptin analogues. J Med Chem 36:1084-9 (1993) [PubMed]  Article 
Target
Name:
Plasminogen
Synonyms:
Activation peptide | PLG | PLMN_BOVIN | Plasmin heavy chain A | Plasmin heavy chain A, short form | Plasmin light chain B
Type:
PROTEIN
Mol. Mass.:
91228.25
Organism:
Bos taurus
Description:
ChEMBL_222778
Residue:
812
Sequence:
MLPASPKMEHKAVVFLLLLFLKSGLGDLLDDYVNTQGASLLSLSRKNLAGRSVEDCAAKCEEETDFVCRAFQYHSKEQQCVVMAENSKNTPVFRMRDVILYEKRIYLLECKTGNGQTYRGTTAETKSGVTCQKWSATSPHVPKFSPEKFPLAGLEENYCRNPDNDENGPWCYTTDPDKRYDYCDIPECEDKCMHCSGENYEGKIAKTMSGRDCQAWDSQSPHAHGYIPSKFPNKNLKMNYCRNPDGEPRPWCFTTDPQKRWEFCDIPRCTTPPPSSGPKYQCLKGTGKNYGGTVAVTESGHTCQRWSEQTPHKHNRTPENFPCKNLEENYCRNPNGEKAPWCYTTNSEVRWEYCTIPSCESSPLSTERMDVPVPPEQTPVPQDCYHGNGQSYRGTSSTTITGRKCQSWSSMTPHRHLKTPENYPNAGLTMNYCRNPDADKSPWCYTTDPRVRWEFCNLKKCSETPEQVPAAPQAPGVENPPEADCMIGTGKSYRGKKATTVAGVPCQEWAAQEPHQHSIFTPETNPQSGLERNYCRNPDGDVNGPWCYTMNPRKPFDYCDVPQCESSFDCGKPKVEPKKCSGRIVGGCVSKPHSWPWQVSLRRSSRHFCGGTLISPKWVLTAAHCLDNILALSFYKVILGAHNEKVREQSVQEIPVSRLFREPSQADIALLKLSRPAIITKEVIPACLPPPNYMVAARTECYITGWGETQGTFGEGLLKEAHLPVIENKVCNRNEYLDGRVKPTELCAGHLIGGTDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCARPNKPGVYVRVSPYVPWIEETMRRN
  
Inhibitor
Name:
BDBM50046896
Synonyms:
2-Acetylamino-4-methyl-pentanoic acid [1-(1-formyl-4-guanidino-butylcarbamoyl)-2-phenyl-ethyl]-amide | CHEMBL2373053
Type:
Small organic molecule
Emp. Form.:
C23H36N6O4
Mol. Mass.:
460.5697
SMILES:
[#6]-[#6](-[#6])-[#6]-[#6@H](-[#7]-[#6](-[#6])=O)-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccccc1)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6]=O |r|
Structure:
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