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Target
Vasopressin V2 receptor
Ligand
BDBM50030080
Substrate
n/a
Meas. Tech.
ChEMBL_215172 (CHEMBL821345)
Kd
130±n/a nM
Citation
 Pavo, I; Slaninova, J; Klein, U; Fahrenholz, F Enhanced selectivity of oxytocin antagonists containing sarcosine in position 7. J Med Chem 37:255-9 (1994) [PubMed]  Article 
Target
Name:
Vasopressin V2 receptor
Synonyms:
AVPR2 | V2R_BOVIN | VASOPRESSIN V2 | Vasopressin V2 receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
40248.83
Organism:
BOVINE
Description:
VASOPRESSIN V2 AVPR2 BOVINE::P48044
Residue:
370
Sequence:
MFMASTTSAVPWHLSQPTPAGNGSEGELLTARDPLLAQAELALLSTVFVAVALSNGLVLGALVRRGRRGRWAPMHVFIGHLCLADLAVALFQVLPQLAWDATDRFRGPDALCRAVKYLQMVGMYASSYMILAMTLDRHRAICRPMLAHRHGGGTHWNRPVLLAWAFSLLFSLPQLFIFAQRDVDGSGVLDCWARFAEPWGLRAYVTWIALMVFVAPALGIAACQVLIFREIHASLGPGPVPRAGGPRRGCRPGSPAEGARVSAAVAKTVKMTLVIVIVYVLCWAPFFLVQLWAAWDPEAPREGPPFVLLMLLASLNSCTNPWIYASFSSSISSELRSLLCCTWRRAPPSPGPQEESCATASSFLAKDTPS
  
Inhibitor
Name:
BDBM50030080
Synonyms:
CHEMBL411420 | [Mca1,D-Tyr(OEt)2,Sar7]AVT
Type:
Small organic molecule
Emp. Form.:
C43H68N14O12S2
Mol. Mass.:
1037.217
SMILES:
CCOc1ccc(C[C@@H]2NC(=O)CCSSC[C@@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC2=O)[C@@H](C)CC)C(=O)N(C)CC(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(N)=O)cc1
Structure:
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