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Target
Vasopressin V2 receptor
Ligand
BDBM50030089
Substrate
n/a
Meas. Tech.
ChEMBL_215172 (CHEMBL821345)
Kd
230±n/a nM
Citation
 Pavo, I; Slaninova, J; Klein, U; Fahrenholz, F Enhanced selectivity of oxytocin antagonists containing sarcosine in position 7. J Med Chem 37:255-9 (1994) [PubMed]  Article 
Target
Name:
Vasopressin V2 receptor
Synonyms:
AVPR2 | V2R_BOVIN | VASOPRESSIN V2 | Vasopressin V2 receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
40248.83
Organism:
BOVINE
Description:
VASOPRESSIN V2 AVPR2 BOVINE::P48044
Residue:
370
Sequence:
MFMASTTSAVPWHLSQPTPAGNGSEGELLTARDPLLAQAELALLSTVFVAVALSNGLVLGALVRRGRRGRWAPMHVFIGHLCLADLAVALFQVLPQLAWDATDRFRGPDALCRAVKYLQMVGMYASSYMILAMTLDRHRAICRPMLAHRHGGGTHWNRPVLLAWAFSLLFSLPQLFIFAQRDVDGSGVLDCWARFAEPWGLRAYVTWIALMVFVAPALGIAACQVLIFREIHASLGPGPVPRAGGPRRGCRPGSPAEGARVSAAVAKTVKMTLVIVIVYVLCWAPFFLVQLWAAWDPEAPREGPPFVLLMLLASLNSCTNPWIYASFSSSISSELRSLLCCTWRRAPPSPGPQEESCATASSFLAKDTPS
  
Inhibitor
Name:
BDBM50030089
Synonyms:
CHEMBL384292 | [Mca1,D-Tyr2,Sar7]AVP
Type:
Small organic molecule
Emp. Form.:
C49H70N14O12S2
Mol. Mass.:
1111.297
SMILES:
CN(CC(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(N)=O)C(=O)[C@@H]1CSSC2(CCCCC2)CC(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N1
Structure:
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