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Target
Gag-Pol polyprotein [489-587]
Ligand
BDBM50368889
Substrate
n/a
Meas. Tech.
ChEMBL_157711 (CHEMBL763385)
Ki
45±n/a nM
Citation
 Islam, I; Ng, KY; Chong, KT; McQuade, TJ; Hui, JO; Wilkinson, KF; Rush, BD; Ruwart, MJ; Borchardt, RT; Fisher, JF Evaluation of a vitamin-cloaking strategy for oligopeptide therapeutics: biotinylated HIV-1 protease inhibitors. J Med Chem 37:293-304 (1994) [PubMed]  Article 
Target
Name:
Gag-Pol polyprotein [489-587]
Synonyms:
Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol
Type:
Enzyme Subunit
Mol. Mass.:
10781.16
Organism:
Human immunodeficiency virus type 1
Description:
P04585[489-587]
Residue:
99
Sequence:
PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
  
Inhibitor
Name:
BDBM50368889
Synonyms:
CHEMBL1790790
Type:
Small organic molecule
Emp. Form.:
C37H60N6O6S
Mol. Mass.:
716.974
SMILES:
CC[C@@H](C)[C@H](NC(=O)[C@H](C(C)C)[C@@H](O)[C@H](O)[C@H](CC1CCCCC1)NC(=O)CCCC[C@@H]1SCC2NC(=O)N[C@H]12)C(=O)NCc1ccccn1
Structure:
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