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Target
Carnitine O-acetyltransferase
Ligand
BDBM50037260
Substrate
n/a
Meas. Tech.
ChEMBL_46180 (CHEMBL660926)
Ki
2600000±n/a nM
Citation
 Saeed, A; McMillin, JB; Wolkowicz, PE; Brouillette, WJ 3-Amino-5,5-dimethylhexanoic acid. Synthesis, resolution, and effects on carnitine acyltransferases. J Med Chem 37:3247-51 (1994) [PubMed]  Article 
Target
Name:
Carnitine O-acetyltransferase
Synonyms:
CACP_HUMAN | CAT | CAT1 | CRAT | Carnitine O-acetyltransferase | Carnitine acetylase | Carnitine acetyltransferase
Type:
PROTEIN
Mol. Mass.:
70873.46
Organism:
Homo sapiens (Human)
Description:
ChEMBL_46180
Residue:
626
Sequence:
MLAFAARTVVKPLGFLKPFSLMKASSRFKAHQDALPRLPVPPLQQSLDHYLKALQPIVSEEEWAHTKQLVDEFQASGGVGERLQKGLERRARKTENWLSEWWLKTAYLQYRQPVVIYSSPGVMLPKQDFVDLQGQLRFAAKLIEGVLDFKVMIDNETLPVEYLGGKPLCMNQYYQILSSCRVPGPKQDTVSNFSKTKKPPTHITVVHNYQFFELDVYHSDGTPLTADQIFVQLEKIWNSSLQTNKEPVGILTSNHRNSWAKAYNTLIKDKVNRDSVRSIQKSIFTVCLDATMPRVSEDVYRSHVAGQMLHGGGSRLNSGNRWFDKTLQFIVAEDGSCGLVYEHAAAEGPPIVTLLDYVIEYTKKPELVRSPLVPLPMPKKLRFNITPEIKSDIEKAKQNLSIMIQDLDITVMVFHHFGKDFPKSEKLSPDAFIQMALQLAYYRIYGQACATYESASLRMFHLGRTDTIRSASMDSLTFVKAMDDSSVTEHQKVELLRKAVQAHRGYTDRAIRGEAFDRHLLGLKLQAIEDLVSMPDIFMDTSYAIAMHFHLSTSQVPAKTDCVMFFGPVVPDGYGVCYNPMEAHINFSLSAYNSCAETNAARLAHYLEKALLDMRALLQSHPRAKL
  
Inhibitor
Name:
BDBM50037260
Synonyms:
3-Amino-5,5-dimethyl-hexanoic acid anion
Type:
Small organic molecule
Emp. Form.:
C8H16NO2
Mol. Mass.:
158.2187
SMILES:
CC(C)(C)CC(N)CC([O-])=O
Structure:
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