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Target
Carnitine O-acetyltransferase
Ligand
BDBM50037266
Substrate
n/a
Meas. Tech.
ChEMBL_46180 (CHEMBL660926)
Ki
24000±n/a nM
Citation
 Saeed, A; McMillin, JB; Wolkowicz, PE; Brouillette, WJ 3-Amino-5,5-dimethylhexanoic acid. Synthesis, resolution, and effects on carnitine acyltransferases. J Med Chem 37:3247-51 (1994) [PubMed]  Article 
Target
Name:
Carnitine O-acetyltransferase
Synonyms:
CACP_HUMAN | CAT | CAT1 | CRAT | Carnitine O-acetyltransferase | Carnitine acetylase | Carnitine acetyltransferase
Type:
PROTEIN
Mol. Mass.:
70873.46
Organism:
Homo sapiens (Human)
Description:
ChEMBL_46180
Residue:
626
Sequence:
MLAFAARTVVKPLGFLKPFSLMKASSRFKAHQDALPRLPVPPLQQSLDHYLKALQPIVSEEEWAHTKQLVDEFQASGGVGERLQKGLERRARKTENWLSEWWLKTAYLQYRQPVVIYSSPGVMLPKQDFVDLQGQLRFAAKLIEGVLDFKVMIDNETLPVEYLGGKPLCMNQYYQILSSCRVPGPKQDTVSNFSKTKKPPTHITVVHNYQFFELDVYHSDGTPLTADQIFVQLEKIWNSSLQTNKEPVGILTSNHRNSWAKAYNTLIKDKVNRDSVRSIQKSIFTVCLDATMPRVSEDVYRSHVAGQMLHGGGSRLNSGNRWFDKTLQFIVAEDGSCGLVYEHAAAEGPPIVTLLDYVIEYTKKPELVRSPLVPLPMPKKLRFNITPEIKSDIEKAKQNLSIMIQDLDITVMVFHHFGKDFPKSEKLSPDAFIQMALQLAYYRIYGQACATYESASLRMFHLGRTDTIRSASMDSLTFVKAMDDSSVTEHQKVELLRKAVQAHRGYTDRAIRGEAFDRHLLGLKLQAIEDLVSMPDIFMDTSYAIAMHFHLSTSQVPAKTDCVMFFGPVVPDGYGVCYNPMEAHINFSLSAYNSCAETNAARLAHYLEKALLDMRALLQSHPRAKL
  
Inhibitor
Name:
BDBM50037266
Synonyms:
(2-Acetylamino-3-carboxy-propyl)-trimethyl-ammonium | CHEMBL36063
Type:
Small organic molecule
Emp. Form.:
C9H18N2O3
Mol. Mass.:
202.2508
SMILES:
CC(=O)NC(CC([O-])=O)C[N+](C)(C)C
Structure:
Search PDB for entries with ligand similarity: