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Target
Carnitine O-acetyltransferase
Ligand
BDBM50037270
Substrate
n/a
Meas. Tech.
ChEMBL_46180 (CHEMBL660926)
Ki
4000000±n/a nM
Citation
 Saeed, A; McMillin, JB; Wolkowicz, PE; Brouillette, WJ 3-Amino-5,5-dimethylhexanoic acid. Synthesis, resolution, and effects on carnitine acyltransferases. J Med Chem 37:3247-51 (1994) [PubMed]  Article 
Target
Name:
Carnitine O-acetyltransferase
Synonyms:
CACP_HUMAN | CAT | CAT1 | CRAT | Carnitine O-acetyltransferase | Carnitine acetylase | Carnitine acetyltransferase
Type:
PROTEIN
Mol. Mass.:
70873.46
Organism:
Homo sapiens (Human)
Description:
ChEMBL_46180
Residue:
626
Sequence:
MLAFAARTVVKPLGFLKPFSLMKASSRFKAHQDALPRLPVPPLQQSLDHYLKALQPIVSEEEWAHTKQLVDEFQASGGVGERLQKGLERRARKTENWLSEWWLKTAYLQYRQPVVIYSSPGVMLPKQDFVDLQGQLRFAAKLIEGVLDFKVMIDNETLPVEYLGGKPLCMNQYYQILSSCRVPGPKQDTVSNFSKTKKPPTHITVVHNYQFFELDVYHSDGTPLTADQIFVQLEKIWNSSLQTNKEPVGILTSNHRNSWAKAYNTLIKDKVNRDSVRSIQKSIFTVCLDATMPRVSEDVYRSHVAGQMLHGGGSRLNSGNRWFDKTLQFIVAEDGSCGLVYEHAAAEGPPIVTLLDYVIEYTKKPELVRSPLVPLPMPKKLRFNITPEIKSDIEKAKQNLSIMIQDLDITVMVFHHFGKDFPKSEKLSPDAFIQMALQLAYYRIYGQACATYESASLRMFHLGRTDTIRSASMDSLTFVKAMDDSSVTEHQKVELLRKAVQAHRGYTDRAIRGEAFDRHLLGLKLQAIEDLVSMPDIFMDTSYAIAMHFHLSTSQVPAKTDCVMFFGPVVPDGYGVCYNPMEAHINFSLSAYNSCAETNAARLAHYLEKALLDMRALLQSHPRAKL
  
Inhibitor
Name:
BDBM50037270
Synonyms:
(2-Amino-3-carboxy-propyl)-trimethyl-ammonium | 3-amino-4-trimethylammonio-(3R)-butanoate | CHEMBL33544
Type:
Small organic molecule
Emp. Form.:
C7H16N2O2
Mol. Mass.:
160.2141
SMILES:
C[N+](C)(C)CC(N)CC([O-])=O
Structure:
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