Reaction Details Report a problem with these data
Target
Serine protease 1
Ligand
BDBM50037979
Substrate
n/a
Meas. Tech.
ChEMBL_212378 (CHEMBL878759)
Ki
8600±n/a nM
Citation
 Hilpert, K; Ackermann, J; Banner, DW; Gast, A; Gubernator, K; Hadváry, P; Labler, L; Müller, K; Schmid, G; Tschopp, TB Design and synthesis of potent and highly selective thrombin inhibitors. J Med Chem 37:3889-901 (1994) [PubMed]  Article 
Target
Name:
Serine protease 1
Synonyms:
Beta-Trypsin | Cationic trypsin | PRSS1 | TRP1 | TRY1 | TRY1_BOVIN | TRYP1 | Trypsin | Trypsin I
Type:
Enzyme
Mol. Mass.:
25790.52
Organism:
Bos taurus (bovine)
Description:
P00760
Residue:
246
Sequence:
MKTFIFLALLGAAVAFPVDDDDKIVGGYTCGANTVPYQVSLNSGYHFCGGSLINSQWVVSAAHCYKSGIQVRLGEDNINVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLNSRVASISLPTSCASAGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQITSNMFCAGYLEGGKDSCQGDSGGPVVCSGKLQGIVSWGSGCAQKNKPGVYTKVCNYVSWIKQTIASN
  
Inhibitor
Name:
BDBM50037979
Synonyms:
CHEMBL539559 | {Benzyl-[(S)-3-[((S)-1-carbamimidoyl-piperidin-3-ylmethyl)-carbamoyl]-2-(naphthalene-2-sulfonylamino)-propionyl]-amino}-acetic acid ethyl ester; hydrochloride
Type:
Small organic molecule
Emp. Form.:
C32H40N6O6S
Mol. Mass.:
636.762
SMILES:
CCOC(=O)CN(Cc1ccccc1)C(=O)[C@H](CC(=O)NC[C@@H]1CCCN(C1)C(N)=N)NS(=O)(=O)c1ccc2ccccc2c1
Structure:
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