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Target
D(2) dopamine receptor
Ligand
BDBM50038283
Substrate
n/a
Meas. Tech.
ChEMBL_59903 (CHEMBL671809)
EC50
>1000±n/a nM
Citation
 Wustrow, DJ; Wise, LD; Cody, DM; MacKenzie, RG; Georgic, LM; Pugsley, TA; Heffner, TG Studies of the active conformation of a novel series of benzamide dopamine D2 agonists. J Med Chem 37:4251-7 (1995) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
D(2) dopamine receptor | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | DRD2_HUMAN | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like | d2
Type:
Cell-surface receptors
Mol. Mass.:
50647.10
Organism:
Homo sapiens (Human)
Description:
P14416
Residue:
443
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC
  
Inhibitor
Name:
BDBM50038283
Synonyms:
CHEMBL337848 | N-[(2S,4aS,6R,8aR)-6-(4-Pyridin-2-yl-piperazin-1-yl)-decahydro-naphthalen-2-yl]-benzamide
Type:
Small organic molecule
Emp. Form.:
C26H34N4O
Mol. Mass.:
418.5744
SMILES:
O=C(N[C@H]1CC[C@H]2C[C@@H](CC[C@@H]2C1)N1CCN(CC1)c1ccccn1)c1ccccc1
Structure:
Search PDB for entries with ligand similarity: