Reaction Details
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Type 1 InsP3 receptor isoform S2
Ligand
BDBM50040909
Substrate
n/a
Meas. Tech.
ChEMBL_90091 (CHEMBL702008)
pH
6.8±n/a
IC50
9114±n/a nM
Comments
extracted
Citation
Kozikowski, AP; Fauq, AH; Wilcox, RA; Challiss, RA; Nahorski, SR The novel Ins(1,4,5)P3 analogue 3-amino-3-deoxy-Ins(1,4,5)P3: a pH-dependent Ins(1,4,5)P3 receptor partial agonist in SH-SY5Y neuroblastoma cells. J Med Chem 37:868-72 (1994) [PubMed] Article More Info.:
Target
Name:
Type 1 InsP3 receptor isoform S2
Synonyms:
n/a
Type:
PROTEIN
Mol. Mass.:
19087.24
Organism:
Sus scrofa
Description:
ChEMBL_90089
Residue:
174
Sequence:
FICKLIKHTKQLLEENEEKLCIKVLQTLREMMTKDRGYGEKLISIDELDNAELPQAPDSENSTEQELEPSPPLRQLEDHKRGEALRQILVNRYYGNIRPSGRRESLTSFGNGPLSPGGPGKPGGGGGGSGSSSMSRGEMSLAEVQCHLDKEGASNLVIDLIMNASSDRVFHESI
Inhibitor
Name:
BDBM50040909
Synonyms:
D-3-amino-3-deoxy-myo-inositol 1,4,5-trisphosphorothioate
Type:
Small organic molecule
Emp. Form.:
C6H10NO14P3
Mol. Mass.:
413.0665
SMILES:
NC1C(O)C(OP([O-])([O-])=O)C(O)C(OP([O-])([O-])=O)C1OP([O-])([O-])=O
Structure:
