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Target
Glutamyl aminopeptidase
Ligand
BDBM50036825
Substrate
n/a
Meas. Tech.
ChEMBL_32828 (CHEMBL646206)
Ki
2400±n/a nM
Citation
 Chauvel, EN; Coric, P; Llorens-Cortès, C; Wilk, S; Roques, BP; Fournié-Zaluski, MC Investigation of the active site of aminopeptidase A using a series of new thiol-containing inhibitors. J Med Chem 37:1339-46 (1994) [PubMed]  Article 
Target
Name:
Glutamyl aminopeptidase
Synonyms:
AMPE_HUMAN | AP-A | Aminopeptidase A | CD_antigen=CD249 | Differentiation antigen gp160 | EAP | ENPEP | Glutamyl aminopeptidase
Type:
PROTEIN
Mol. Mass.:
109226.47
Organism:
Homo sapiens (Human)
Description:
ChEMBL_32829
Residue:
957
Sequence:
MNFAEREGSKRYCIQTKHVAILCAVVVGVGLIVGLAVGLTRSCDSSGDGGPGTAPAPSHLPSSTASPSGPPAQDQDICPASEDESGQWKNFRLPDFVNPVHYDLHVKPLLEEDTYTGTVSISINLSAPTRYLWLHLRETRITRLPELKRPSGDQVQVRRCFEYKKQEYVVVEAEEELTPSSGDGLYLLTMEFAGWLNGSLVGFYRTTYTENGQVKSIVATDHEPTDARKSFPCFDEPNKKATYTISITHPKEYGALSNMPVAKEESVDDKWTRTTFEKSVPMSTYLVCFAVHQFDSVKRISNSGKPLTIYVQPEQKHTAEYAANITKSVFDYFEEYFAMNYSLPKLDKIAIPDFGTGAMENWGLITYRETNLLYDPKESASSNQQRVATVVAHELVHQWFGNIVTMDWWEDLWLNEGFASFFEFLGVNHAETDWQMRDQMLLEDVLPVQEDDSLMSSHPIIVTVTTPDEITSVFDGISYSKGSSILRMLEDWIKPENFQKGCQMYLEKYQFKNAKTSDFWAALEEASRLPVKEVMDTWTRQMGYPVLNVNGVKNITQKRFLLDPRANPSQPPSDLGYTWNIPVKWTEDNITSSVLFNRSEKEGITLNSSNPSGNAFLKINPDHIGFYRVNYEVATWDSIATALSLNHKTFSSADRASLIDDAFALARAQLLDYKVALNLTKYLKREENFLPWQRVISAVTYIISMFEDDKELYPMIEEYFQGQVKPIADSLGWNDAGDHVTKLLRSSVLGFACKMGDREALNNASSLFEQWLNGTVSLPVNLRLLVYRYGMQNSGNEISWNYTLEQYQKTSLAQEKEKLLYGLASVKNVTLLSRYLDLLKDTNLIKTQDVFTVIRYISYNSYGKNMAWNWIQLNWDYLVNRYTLNNRNLGRIVTIAEPFNTELQLWQMESFFAKYPQAGAGEKPREQVLETVKNNIEWLKQHRNTIREWFFNLLESG
  
Inhibitor
Name:
BDBM50036825
Synonyms:
1-(3-Carboxy-phenyl)-2-mercapto-ethyl-ammonium | 3-(1-Amino-2-mercapto-ethyl)-benzoic acid | CHEMBL281321
Type:
Small organic molecule
Emp. Form.:
C9H11NO2S
Mol. Mass.:
197.254
SMILES:
NC(CS)c1cccc(c1)C(O)=O
Structure:
Search PDB for entries with ligand similarity: