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Target
D(2) dopamine receptor
Ligand
BDBM50029258
Substrate
n/a
Meas. Tech.
ChEMBL_62394 (CHEMBL672949)
Ki
300±n/a nM
Citation
 Scott, MK; Baxter, EW; Bennett, DJ; Boyd, RE; Blum, PS; Codd, EE; Kukla, MJ; Malloy, E; Maryanoff, BE; Maryanoff, CA Piperazinylalkyl heterocycles as potential antipsychotic agents. J Med Chem 38:4198-210 (1995) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2_RAT | Dopamine D2 receptor | Dopamine2-like | Drd2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
50931.60
Organism:
Rattus norvegicus (rat)
Description:
P61169
Residue:
444
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC
  
Inhibitor
Name:
BDBM50029258
Synonyms:
3.303211-(5-{2-[4-(2-Isopropoxy-phenyl)-piperazin-1-yl]-ethyl}-1-methyl-1H-pyrrol-2-yl)-2-morpholin-4-yl-ethane-1,2-dione;succinate
Type:
Small organic molecule
Emp. Form.:
C26H36N4O4
Mol. Mass.:
468.5884
SMILES:
CC(C)Oc1ccccc1N1CCN(CCc2ccc(C(=O)C(=O)N3CCOCC3)n2C)CC1
Structure:
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