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Target
D(2) dopamine receptor
Ligand
BDBM50052569
Substrate
n/a
Meas. Tech.
ChEMBL_58564 (CHEMBL667499)
IC50
1060±n/a nM
Citation
 Perrone, R; Berardi, F; Leopoldo, M; Tortorella, V; Fornaretto, MG; Caccia, C; McArthur, RA 1-aryl-4-[(1-tetralinyl)alkyl]piperazines: alkylamido and alkylamino derivatives. Synthesis, 5-HT1A receptor affinity, and selectivity. 3. J Med Chem 39:3195-202 (1996) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2_RAT | Dopamine D2 receptor | Dopamine2-like | Drd2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
50931.60
Organism:
Rattus norvegicus (rat)
Description:
P61169
Residue:
444
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC
  
Inhibitor
Name:
BDBM50052569
Synonyms:
CHEMBL107486 | {3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-propyl}-(5-methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-amine
Type:
Small organic molecule
Emp. Form.:
C25H35N3O2
Mol. Mass.:
409.5643
SMILES:
COc1cccc2C(CCCc12)NCCCN1CCN(CC1)c1ccccc1OC
Structure:
Search PDB for entries with ligand similarity: