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Target
D(1) dopamine receptor
Ligand
BDBM50004822
Substrate
n/a
Meas. Tech.
ChEMBL_59005 (CHEMBL880003)
EC50
950±n/a nM
Citation
 Michaelides, MR; Hong, Y; DiDomenico, S; Bayburt, EK; Asin, KE; Britton, DR; Lin, CW; Shiosaki, K Substituted hexahydrobenzo[f]thieno[c]quinolines as dopamine D1-selective agonists: synthesis and biological evaluation in vitro and in vivo. J Med Chem 40:1585-99 (1997) [PubMed]  Article 
Target
Name:
D(1) dopamine receptor
Synonyms:
D(1) dopamine receptor | DRD1_CARAU | Dopamine D1 receptor
Type:
n/a
Mol. Mass.:
40664.04
Organism:
Carassius auratus
Description:
n/a
Residue:
363
Sequence:
MAVLDLNLTTVIDSGFMESDRSVRVLTGCFLSVLILSTLLGNTLVCAAVTKFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVTEVAGFWPFGAFCDIWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTPRVAFVMISGAWTLSVLISFIPVQLKWHKAQPIGFLEVNASRRDLPTDNCDSSLNRTYAISSSLISFYIPVAIMIVTYTQIYRIAQKQIRRISALERAAESAQIRHDSMGSGSNMDLESSFKLSFKRETKVLKTLSVIMGVFVCCWLPFFILNCMVPFCKRTSNGLPCISPTTFDVFVWFGWANSSLNPIIYAFNADFRRAFAILLGCQRLCPGSISMETPSLNKN
  
Inhibitor
Name:
BDBM50004822
Synonyms:
(R)-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol | (R)-7,8-Dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepinium | 1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol | 1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol(SKF38393) | 7,8-Dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepinium(R(+)SKF38393) | CHEMBL1467585 | CHEMBL24077 | R(+)SKF 383931-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol | SK&F-383933 | SK-38393 | SK-383933 | SKF 38393 | SKF 38393 (+)
Type:
Small organic molecule
Emp. Form.:
C16H17NO2
Mol. Mass.:
255.3117
SMILES:
Oc1cc2CCNC[C@H](c3ccccc3)c2cc1O
Structure:
Search PDB for entries with ligand similarity: