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Target
D(1) dopamine receptor
Ligand
BDBM50010686
Substrate
n/a
Meas. Tech.
ChEMBL_59005 (CHEMBL880003)
EC50
88±n/a nM
Citation
 Michaelides, MR; Hong, Y; DiDomenico, S; Bayburt, EK; Asin, KE; Britton, DR; Lin, CW; Shiosaki, K Substituted hexahydrobenzo[f]thieno[c]quinolines as dopamine D1-selective agonists: synthesis and biological evaluation in vitro and in vivo. J Med Chem 40:1585-99 (1997) [PubMed]  Article 
Target
Name:
D(1) dopamine receptor
Synonyms:
D(1) dopamine receptor | DRD1_CARAU | Dopamine D1 receptor
Type:
n/a
Mol. Mass.:
40664.04
Organism:
Carassius auratus
Description:
n/a
Residue:
363
Sequence:
MAVLDLNLTTVIDSGFMESDRSVRVLTGCFLSVLILSTLLGNTLVCAAVTKFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVTEVAGFWPFGAFCDIWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTPRVAFVMISGAWTLSVLISFIPVQLKWHKAQPIGFLEVNASRRDLPTDNCDSSLNRTYAISSSLISFYIPVAIMIVTYTQIYRIAQKQIRRISALERAAESAQIRHDSMGSGSNMDLESSFKLSFKRETKVLKTLSVIMGVFVCCWLPFFILNCMVPFCKRTSNGLPCISPTTFDVFVWFGWANSSLNPIIYAFNADFRRAFAILLGCQRLCPGSISMETPSLNKN
  
Inhibitor
Name:
BDBM50010686
Synonyms:
(6aR,12bS)-10,11-Dihydroxy-5,6,6a,7,8,12b-hexahydro-benzo[a]phenanthridinium | (6aR,12bS)-5,6,6a,7,8,12b-Hexahydro-benzo[a]phenanthridine-10,11-diol | 10,11-Dihydroxy-5,6,6a,7,8,12b-hexahydro-benzo[a]phenanthridinium(DHX) | 5,6,6a,7,8,12b-Hexahydro-benzo[a]phenanthridine-10,11-diol | CHEMBL25856 | dihydrexidine
Type:
Small organic molecule
Emp. Form.:
C17H17NO2
Mol. Mass.:
267.3224
SMILES:
Oc1cc2CC[C@H]3NCc4ccccc4[C@@H]3c2cc1O
Structure:
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