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Target
Delta-type opioid receptor
Ligand
BDBM50058658
Substrate
n/a
Meas. Tech.
ChEMBL_146320 (CHEMBL757529)
Ki
2.7±n/a nM
Citation
 Farouz-Grant, F; Portoghese, PS Pyrrolomorphinans as delta opioid receptor antagonists. The role of steric hindrance in conferring selectivity. J Med Chem 40:1977-81 (1997) [PubMed]  Article 
Target
Name:
Delta-type opioid receptor
Synonyms:
DOR-1 | K56 | MSL-2 | OPIATE Delta | OPRD_MOUSE | Opioid receptors; mu and delta | Oprd1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
40577.25
Organism:
MOUSE
Description:
P32300
Residue:
372
Sequence:
MELVPSARAELQSSPLVNLSDAFPSAFPSAGANASGSPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKLKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTQPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDINRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRTPCGRQEPGSLRRPRQATTRERVTACTPSDGPGGGAAA
  
Inhibitor
Name:
BDBM50058658
Synonyms:
18-cyclopropylmethyl-5-phenyl-10-oxa-7,18-diazahexacyclo[9.9.1.01,9.02,17.04,8.015,21]henicosa-4(8),5,11,13,15(21)-pentaene-2,12-diol | CHEMBL305146
Type:
Small organic molecule
Emp. Form.:
C28H28N2O3
Mol. Mass.:
440.5335
SMILES:
Oc1ccc2CC3N(CC4CC4)CCC45[C@@H](Oc1c24)c1[nH]cc(c1C[C@@]35O)-c1ccccc1 |TLB:26:25:18.4.5:7.13.12,THB:8:7:25:18.4.5,17:18:25:7.13.12|
Structure:
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