Reaction Details Report a problem with these data
Target
5-hydroxytryptamine receptor 1D
Ligand
BDBM50016913
Substrate
n/a
Meas. Tech.
ChEMBL_2005 (CHEMBL617098)
Ki
112±n/a nM
Citation
 Ismaiel, AM; Dukat, M; Law, H; Kamboj, R; Fan, E; Lee, DK; Mazzocco, L; Buekschkens, D; Teitler, M; Pierson, ME; Glennon, RA 2-(1-Naphthyloxy)ethylamines with enhanced affinity for human 5-HT1D beta (h5-HT1B) serotonin receptors. J Med Chem 40:4415-9 (1998) [PubMed]  Article 
Target
Name:
5-hydroxytryptamine receptor 1D
Synonyms:
5-HT-1D | 5-HT-1D-alpha | 5-HT1D | 5-hydroxytryptamine receptor 1D (5-HT1D) | 5HT1D_HUMAN | HTR1D | HTR1DA | HTRL | Serotonin (5-HT) receptor | Serotonin Receptor 1D
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
41920.63
Organism:
Homo sapiens (Human)
Description:
Receptor binding assays were performed using human clone stably expressed in CHO cells.
Residue:
377
Sequence:
MSPLNQSAEGLPQEASNRSLNATETSEAWDPRTLQALKISLAVVLSVITLATVLSNAFVLTTILLTRKLHTPANYLIGSLATTDLLVSILVMPISIAYTITHTWNFGQILCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAATMIAIVWAISICISIPPLFWRQAKAQEEMSDCLVNTSQISYTIYSTCGAFYIPSVLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNSSLHEGHSHSAGSPLFFNHVKIKLADSALERKRISAARERKATKILGIILGAFIICWLPFFVVSLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKIVPFRKAS
  
Inhibitor
Name:
BDBM50016913
Synonyms:
Butyl-ethyl-[2-(naphthalen-1-yloxy)-ethyl]-amine | CHEMBL138907
Type:
Small organic molecule
Emp. Form.:
C18H25NO
Mol. Mass.:
271.3972
SMILES:
CCCCN(CC)CCOc1cccc2ccccc12
Structure:
Search PDB for entries with ligand similarity: