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Target
Cannabinoid receptor 1
Ligand
BDBM50056461
Substrate
n/a
Meas. Tech.
ChEMBL_46297 (CHEMBL661066)
Ki
1820±n/a nM
Citation
 Sheskin, T; Hanus, L; Slager, J; Vogel, Z; Mechoulam, R Structural requirements for binding of anandamide-type compounds to the brain cannabinoid receptor. J Med Chem 40:659-67 (1997) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 1
Synonyms:
CANN6 | CANNABINOID CB1 | CB-R | CB1 | CNR | CNR1 | CNR1_HUMAN | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cannabinoid receptor 1 (brain)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
52868.96
Organism:
Homo sapiens (Human)
Description:
P21554
Residue:
472
Sequence:
MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQEKMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQPLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
  
Inhibitor
Name:
BDBM50056461
Synonyms:
(5Z,8Z,11Z,14Z)-Icosa-5,8,11,14-tetraenoic acid (2-methoxy-ethyl)-amide | CHEMBL75591 | Icosa-5,8,11,14-tetraenoic acid (2-methoxy-ethyl)-amide (0609)
Type:
Small organic molecule
Emp. Form.:
C23H39NO2
Mol. Mass.:
361.5613
SMILES:
CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)NCCOC
Structure:
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