Reaction Details Report a problem with these data
Target
Adenosine receptor A1
Ligand
BDBM50267393
Substrate
n/a
Meas. Tech.
ChEMBL_28391 (CHEMBL639538)
EC50
26±n/a nM
Citation
 van der Wenden, EM; Carnielli, M; Roelen, HC; Lorenzen, A; von Frijtag Drabbe Künzel, JK; IJzerman, AP 5'-substituted adenosine analogs as new high-affinity partial agonists for the adenosine A1 receptor. J Med Chem 41:102-8 (1998) [PubMed]  Article 
Target
Name:
Adenosine receptor A1
Synonyms:
AA1R_RAT | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | Adenosine A1 receptor (A1) | Adenosine receptor | Adenosine receptors A1 | Adora1
Type:
Protein
Mol. Mass.:
36704.13
Organism:
Rattus norvegicus (rat)
Description:
n/a
Residue:
326
Sequence:
MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED
  
Inhibitor
Name:
BDBM50267393
Synonyms:
CHEMBL477444 | N6-Cyclopentyl-9H-(5-chloro-5-deoxy-beta-D-ribofuranosyl)adenine
Type:
Small organic molecule
Emp. Form.:
C15H20ClN5O3
Mol. Mass.:
353.804
SMILES:
O[C@@H]1[C@@H](CCl)O[C@H]([C@@H]1O)n1cnc2c(NC3CCCC3)ncnc12 |r|
Structure:
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