Reaction Details Report a problem with these data
Target
Sigma non-opioid intracellular receptor 1
Ligand
BDBM50369355
Substrate
n/a
Meas. Tech.
ChEMBL_226562 (CHEMBL848641)
Ki
>10000±n/a nM
Citation
 Berg, S; Larsson, LG; Rényi, L; Ross, SB; Thorberg, SO; Thorell-Svantesson, G (R)-(+)-2-[[[3-(Morpholinomethyl)-2H-chromen-8-yl]oxy]methyl] morpholine methanesulfonate: a new selective rat 5-hydroxytryptamine1B receptor antagonist. J Med Chem 41:1934-42 (1998) [PubMed]  Article 
Target
Name:
Sigma non-opioid intracellular receptor 1
Synonyms:
Opioid receptor | Oprs1 | SGMR1_RAT | Sigma | Sigma non-opioid intracellular receptor 1 | Sigma opioid receptor | Sigma-1 | Sigmar1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
25266.54
Organism:
RAT
Description:
Q9R0C9
Residue:
223
Sequence:
MPWAVGRRWAWITLFLTIVAVLIQAVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSRLIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSHGHSGRYWAEISDTIISGTFHQWREGTTKSEVYYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPSTLAFALSDTIFSTQDFLTLFYTLRAYARGLRLELTTYLFGQDP
  
Inhibitor
Name:
BDBM50369355
Synonyms:
CHEMBL1202783
Type:
Small organic molecule
Emp. Form.:
C19H26N2O4
Mol. Mass.:
346.4207
SMILES:
C(Oc1cccc2C=C(CN3CCOCC3)COc12)[C@@H]1CNCCO1 |r,t:7|
Structure:
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