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Target
D(2) dopamine receptor
Ligand
BDBM50067816
Substrate
n/a
Meas. Tech.
ChEMBL_61770 (CHEMBL672947)
IC50
3500±n/a nM
Citation
 Efange, SM; Mash, DC; Khare, AB; Ouyang, Q Modified ibogaine fragments: synthesis and preliminary pharmacological characterization of 3-ethyl-5-phenyl-1,2,3,4,5, 6-hexahydroazepino[4,5-b]benzothiophenes. J Med Chem 41:4486-91 (1998) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2_RAT | Dopamine D2 receptor | Dopamine2-like | Drd2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
50931.60
Organism:
Rattus norvegicus (rat)
Description:
P61169
Residue:
444
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC
  
Inhibitor
Name:
BDBM50067816
Synonyms:
9-(3-Bromo-phenyl)-7-ethyl-6,7,8,9-tetrahydro-5H-10-thia-7-aza-benzo[a]azulene | CHEMBL139081
Type:
Small organic molecule
Emp. Form.:
C20H20BrNS
Mol. Mass.:
386.349
SMILES:
CCN1CCc2c(sc3ccccc23)C(C1)c1cccc(Br)c1
Structure:
Search PDB for entries with ligand similarity: