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Target
Muscarinic acetylcholine receptor M2
Ligand
BDBM50062447
Substrate
n/a
Meas. Tech.
ChEMBL_140185 (CHEMBL744902)
Ki
71000±n/a nM
Citation
 Rival, Y; Hoffmann, R; Didier, B; Rybaltchenko, V; Bourguignon, JJ; Wermuth, CG 5-HT3 antagonists derived from aminopyridazine-type muscarinic M1 agonists. J Med Chem 41:311-7 (1998) [PubMed]  Article 
Target
Name:
Muscarinic acetylcholine receptor M2
Synonyms:
ACM2_RAT | Cholinergic, muscarinic M2 | Chrm-2 | Chrm2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
51555.53
Organism:
RAT
Description:
P10980
Residue:
466
Sequence:
MNNSTNSSNNGLAITSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNYFLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQFFSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKEKKEPVANQDPVSPSLVQGRIVKPNNNNMPGGDGGLEHNKIQNGKAPRDGVTENCVQGEEKESSNDSTSVSAVASNMRDDEITQDENTVSTSLGHSRDDNSKQTCIKIVTKAQKGDVCTPTSTTVELVGSSGQNGDEKQNIVARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNTVWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR
  
Inhibitor
Name:
BDBM50062447
Synonyms:
3-(4-Methyl-piperazin-1-yl)-6-phenyl-pyridazine; hydrochloride | CHEMBL545506
Type:
Small organic molecule
Emp. Form.:
C15H18N4
Mol. Mass.:
254.3302
SMILES:
CN1CCN(CC1)c1ccc(nn1)-c1ccccc1
Structure:
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