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Target
Muscarinic acetylcholine receptor M1
Ligand
BDBM50062451
Substrate
n/a
Meas. Tech.
ChEMBL_138956 (CHEMBL742768)
Ki
62000±n/a nM
Citation
 Rival, Y; Hoffmann, R; Didier, B; Rybaltchenko, V; Bourguignon, JJ; Wermuth, CG 5-HT3 antagonists derived from aminopyridazine-type muscarinic M1 agonists. J Med Chem 41:311-7 (1998) [PubMed]  Article 
Target
Name:
Muscarinic acetylcholine receptor M1
Synonyms:
ACM1_RAT | Cholinergic, muscarinic M1 | Chrm-1 | Chrm1 | cholinergic receptor, muscarinic 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
51390.46
Organism:
RAT
Description:
P08482
Residue:
460
Sequence:
MNTSVPPAVSPNITVLAPGKGPWQVAFIGITTGLLSLATVTGNLLVLISFKVNTELKTVNNYFLLSLACADLIIGTFSMNLYTTYLLMGHWALGTLACDLWLALDYVASNASVMNLLLISFDRYFSVTRPLSYRAKRTPRRAALMIGLAWLVSFVLWAPAILFWQYLVGERTVLAGQCYIQFLSQPIITFGTAMAAFYLPVTVMCTLYWRIYRETENRARELAALQGSETPGKGGGSSSSSERSQPGAEGSPESPPGRCCRCCRAPRLLQAYSWKEEEEEDEGSMESLTSSEGEEPGSEVVIKMPMVDSEAQAPTKQPPKSSPNTVKRPTKKGRDRGGKGQKPRGKEQLAKRKTFSLVKEKKAARTLSAILLAFILTWTPYNIMVLVSTFCKDCVPETLWELGYWLCYVNSTVNPMCYALCNKAFRDTFRLLLLCRWDKRRWRKIPKRPGSVHRTPSRQC
  
Inhibitor
Name:
BDBM50062451
Synonyms:
3-(4-Methyl-piperazin-1-yl)-5-phenyl-pyridazine; hydrochloride | CHEMBL540310
Type:
Small organic molecule
Emp. Form.:
C15H18N4
Mol. Mass.:
254.3302
SMILES:
CN1CCN(CC1)c1cc(cnn1)-c1ccccc1
Structure:
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