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Target
Sigma non-opioid intracellular receptor 1
Ligand
BDBM50039197
Substrate
n/a
Meas. Tech.
ChEMBL_201896 (CHEMBL808187)
IC50
44±n/a nM
Citation
 Moriarty, RM; Enache, LA; Zhao, L; Gilardi, R; Mattson, MV; Prakash, O Rigid phencyclidine analogues. Binding to the phencyclidine and sigma 1 receptors. J Med Chem 41:468-77 (1998) [PubMed]  Article 
Target
Name:
Sigma non-opioid intracellular receptor 1
Synonyms:
Opioid receptor | Oprs1 | SGMR1_RAT | Sigma | Sigma non-opioid intracellular receptor 1 | Sigma opioid receptor | Sigma-1 | Sigmar1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
25266.54
Organism:
RAT
Description:
Q9R0C9
Residue:
223
Sequence:
MPWAVGRRWAWITLFLTIVAVLIQAVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSRLIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSHGHSGRYWAEISDTIISGTFHQWREGTTKSEVYYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPSTLAFALSDTIFSTQDFLTLFYTLRAYARGLRLELTTYLFGQDP
  
Inhibitor
Name:
BDBM50039197
Synonyms:
1-Phenyl-cyclohexanecarboxylic acid 2-morpholin-4-yl-ethyl ester | CHEMBL305881
Type:
Small organic molecule
Emp. Form.:
C19H27NO3
Mol. Mass.:
317.4226
SMILES:
O=C(OCCN1CCOCC1)C1(CCCCC1)c1ccccc1
Structure:
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