Reaction Details Report a problem with these data
Target
Adenosine receptor A2a
Ligand
BDBM50090697
Substrate
n/a
Meas. Tech.
ChEMBL_31046 (CHEMBL642117)
Ki
100±n/a nM
Citation
 Ferrarini, PL; Mori, C; Manera, C; Martinelli, A; Mori, F; Saccomanni, G; Barili, PL; Betti, L; Giannaccini, G; Trincavelli, L; Lucacchini, A A novel class of highly potent and selective A1 adenosine antagonists: structure-affinity profile of a series of 1,8-naphthyridine derivatives. J Med Chem 43:2814-23 (2000) [PubMed]  Article 
Target
Name:
Adenosine receptor A2a
Synonyms:
A2A adenosine receptor (hA2A) | AA2AR_HUMAN | ADENOSINE A2 | ADENOSINE A2a | ADORA2 | ADORA2A | Adenosine A2A receptor (A2AAR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44716.46
Organism:
Homo sapiens (Human)
Description:
P29274
Residue:
412
Sequence:
MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFRKIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERRPNGYALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGVS
  
Inhibitor
Name:
BDBM50090697
Synonyms:
7-Chloro-2-phenyl-[1,8]naphthyridin-4-ol | 7-chloro-2-phenyl-1,8-naphthyridin-4-ol | CHEMBL97760
Type:
Small organic molecule
Emp. Form.:
C14H9ClN2O
Mol. Mass.:
256.687
SMILES:
Oc1cc(nc2nc(Cl)ccc12)-c1ccccc1
Structure:
Search PDB for entries with ligand similarity: