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Target
D(3) dopamine receptor
Ligand
BDBM50092169
Substrate
n/a
Meas. Tech.
ChEMBL_62437 (CHEMBL676636)
Ki
11±n/a nM
Citation
 van Vliet, LA; Rodenhuis, N; Wikström, H; Pugsley, TA; Serpa, KA; Meltzer, LT; Heffner, TG; Wise, LD; Lajiness, ME; Huff, RM; Svensson, K; Haenen, GR; Bast, A Thiazoloindans and thiazolobenzopyrans: a novel class of orally active central dopamine (partial) agonists. J Med Chem 43:3549-57 (2000) [PubMed]  Article 
Target
Name:
D(3) dopamine receptor
Synonyms:
DOPAMINE D3 | DRD3 | DRD3_HUMAN | Dopamine D3 receptor | Dopamine D3 receptor (D3) | Dopamine D3 receptor (D3R) | Dopamine receptor | Dopamine receptor (D3) | Dopamine receptor D3
Type:
n/a
Mol. Mass.:
44243.43
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
400
Sequence:
MASLSQLSSHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTVCSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQQTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRKLSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
  
Inhibitor
Name:
BDBM50092169
Synonyms:
CHEMBL118636 | N*7*,N*7*-Dipropyl-7,8-dihydro-6H-1-thia-3-aza-as-indacene-2,7-diamine
Type:
Small organic molecule
Emp. Form.:
C16H23N3S
Mol. Mass.:
289.439
SMILES:
CCCN(CCC)C1Cc2ccc3nc(N)sc3c2C1
Structure:
Search PDB for entries with ligand similarity: