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Target
Gamma-aminobutyric acid receptor subunit rho-1
Ligand
BDBM85712
Substrate
n/a
Meas. Tech.
ChEMBL_68703 (CHEMBL682634)
EC50
16000±n/a nM
Citation
 Chebib, M; Johnston, GA GABA-Activated ligand gated ion channels: medicinal chemistry and molecular biology. J Med Chem 43:1427-47 (2000) [PubMed]  Article 
Target
Name:
Gamma-aminobutyric acid receptor subunit rho-1
Synonyms:
GABA receptor rho-1 subunit | GABA-C receptor | GABRR1 | GBRR1_HUMAN
Type:
PROTEIN
Mol. Mass.:
55892.34
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1456653
Residue:
479
Sequence:
MLAVPNMRFGIFLLWWGWVLATESRMHWPGREVHEMSKKGRPQRQRREVHEDAHKQVSPILRRSPDITKSPLTKSEQLLRIDDHDFSMRPGFGGPAIPVGVDVQVESLDSISEVDMDFTMTLYLRHYWKDERLSFPSTNNLSMTFDGRLVKKIWVPDMFFVHSKRSFIHDTTTDNVMLRVQPDGKVLYSLRVTVTAMCNMDFSRFPLDTQTCSLEIESYAYTEDDLMLYWKKGNDSLKTDERISLSQFLIQEFHTTTKLAFYSSTGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVPLGITTVLTMSTIITGVNASMPRVSYIKAVDIYLWVSFVFVFLSVLEYAAVNYLTTVQERKEQKLREKLPCTSGLPPPRTAMLDGNYSDGEVNDLDNYMPENGEKPDRMMVQLTLASERSSPQRKSQRSSYVSMRIDTHAIDKYSRIIFPAAYILFNLIYWSIFS
  
Inhibitor
Name:
BDBM85712
Synonyms:
1H-imidazol-4-ylacetic acid | CAS_645-65-8 | CHEMBL784 | Imidazole-4-acetic acid | NSC_96215
Type:
Small organic molecule
Emp. Form.:
C5H6N2O2
Mol. Mass.:
126.1133
SMILES:
OC(=O)Cc1cnc[nH]1
Structure:
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