Reaction Details Report a problem with these data
Target
2-oxoglutarate receptor 1
Ligand
BDBM50106539
Substrate
n/a
Meas. Tech.
ChEMBL_151406 (CHEMBL754752)
Ki
167±n/a nM
Citation
 Umino, T; Yoshioka, K; Saitoh, Y; Minakawa, N; Nakata, H; Matsuda, A Nucleosides and nucleotides. 200. Reinvestigation of 5'-N-ethylcarboxamidoadenosine derivatives: structure-activity relationships for P(3) purinoceptor-like proteins. J Med Chem 44:208-14 (2001) [PubMed]  Article 
Target
Name:
2-oxoglutarate receptor 1
Synonyms:
G protein-coupled receptor 80 | Gpr80 | OXGR1_RAT | Oxgr1 | P2y15
Type:
PROTEIN
Mol. Mass.:
38385.93
Organism:
Rattus norvegicus
Description:
ChEMBL_151406
Residue:
337
Sequence:
MIETLDSPANDSDFLDYITALENCTDEQISFKMQYLPVIYSIIFLVGFPGNTVAISIYVFKMRPWKSSTIIMLNLALTDLLYLTSLPFLIHYYASGENWIFGDFMCKFIRFGFHFNLYSSILFLTCFSLFRYIVIIHPMSCFSIQKTRWAVVACAGVWVISLVAVMPMTFLITSTTRTNRSACLDLTSSDDLTTIKWYNLILTATTFCLPLLIVTLCYTTIISTLTHGPRTHSCFKQKARRLTILLLLVFYVCFLPFHILRVIRIESRLLSISCSIESHIHEAYIVSRPLAALNTFGNLLLYVVVSNNFQQAFCSAVRCKAIGDLEQAKKDSCSNNP
  
Inhibitor
Name:
BDBM50106539
Synonyms:
(2S,3S,4R,5R)-5-(6-Amino-purin-9-yl)-3,4-dihydroxy-tetrahydro-furan-2-carboxylic acid (2-amino-ethyl)-amide | (2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-(2-aminoethyl)-3,4-dihydroxy-tetrahydrofuran-2-carboxamide | 5'-N-[(2-AMINO)ETHYL CARBOXAMIDO] ADENOSINE | 5-(6-Amino-purin-9-yl)-3,4-dihydroxy-tetrahydro-furan-2-carboxylic acid (2-amino-ethyl)-amide | Adenosine analog, 1 | CHEMBL129903
Type:
Small organic molecule
Emp. Form.:
C12H17N7O4
Mol. Mass.:
323.3079
SMILES:
NCCNC(=O)[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12
Structure:
Search PDB for entries with ligand similarity: