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Target
Adenosine transporter 1
Ligand
BDBM50105120
Substrate
n/a
Meas. Tech.
ChEMBL_149711 (CHEMBL755808)
Ki
410±n/a nM
Citation
 Klenke, B; Stewart, M; Barrett, MP; Brun, R; Gilbert, IH Synthesis and biological evaluation of s-triazine substituted polyamines as potential new anti-trypanosomal drugs. J Med Chem 44:3440-52 (2001) [PubMed]  Article 
Target
Name:
Adenosine transporter 1
Synonyms:
n/a
Type:
PROTEIN
Mol. Mass.:
51044.02
Organism:
Trypanosoma brucei
Description:
ChEMBL_31141
Residue:
463
Sequence:
MLGFDSANEFIVYVTFLFFGMSVVVVTNSIFSMPFFFIEYYKYAQGKPDAKPEDPKFWKHMFTYYSIAAFLVELVLASLMLTPIGRRISVTVRLGVGLVIPIVLVFSVMMVTIVTTTETGAKVTIMLIAIANGVAMTLCDAGNAALIAPFPTKFYSSVVWGIAVCGVVTSFFSIVIKASMGGGYHNMLIQSRIYFGLVMFMQVISCALLVLLRKNPYAQKYAAEFRYAARKGIDDKGADGDEGNGAAKGPADQDDDPHGGDDTDKGNVMTATVDPDTMKDMDQVENITTSQQMLMARVWNVFWRVWPMLFACFMVFFTTFLVYPAVYFAIKADTGDGWYLTIAAALFNLGDFLSRLCLQFKALHVSPRWVLIGTFARMLLIIPLVLCVRSIITGPWLPYILVHAWGFTYGYYGGISQIYAPRTGSLTTAGERSLAANWTIISLLGGIFVGAMFALAVNEGLPK
  
Inhibitor
Name:
BDBM50105120
Synonyms:
CHEMBL542932 | N-{3-[12-(3-Amino-propylamino)-dodecylamino]-propyl}-N'-methyl-[1,3,5]triazine-2,4,6-triaminetetrahydrochloride
Type:
Small organic molecule
Emp. Form.:
C22H47N9
Mol. Mass.:
437.6689
SMILES:
CNc1nc(N)nc(NCCCNCCCCCCCCCCCCNCCCN)n1
Structure:
Search PDB for entries with ligand similarity: