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Target
P2Y purinoceptor 2
Ligand
BDBM18137
Substrate
n/a
Meas. Tech.
ChEMBL_147745 (CHEMBL753285)
EC50
3700±n/a nM
Citation
 Kim, HS; Ravi, RG; Marquez, VE; Maddileti, S; Wihlborg, AK; Erlinge, D; Malmsjö, M; Boyer, JL; Harden, TK; Jacobson, KA Methanocarba modification of uracil and adenine nucleotides: high potency of Northern ring conformation at P2Y1, P2Y2, P2Y4, and P2Y11 but not P2Y6 receptors. J Med Chem 45:208-18 (2001) [PubMed]  Article 
Target
Name:
P2Y purinoceptor 2
Synonyms:
P2Y purinoceptor 2 | Purinergic receptor | P2U purinoceptor 1 | ATP receptor | P2U1 | P2Y2 | P2RY2_HUMAN | P2RY2 | P2RU1 | Purinergic receptor P2Y2
Type:
PROTEIN
Mol. Mass.:
42299.21
Organism:
Human
Description:
ChEMBL_1455361
Residue:
377
Sequence:
MAADLGPWNDTINGTWDGDELGYRCRFNEDFKYVLLPVSYGVVCVPGLCLNAVALYIFLCRLKTWNASTTYMFHLAVSDALYAASLPLLVYYYARGDHWPFSTVLCKLVRFLFYTNLYCSILFLTCISVHRCLGVLRPLRSLRWGRARYARRVAGAVWVLVLACQAPVLYFVTTSARGGRVTCHDTSAPELFSRFVAYSSVMLGLLFAVPFAVILVCYVLMARRLLKPAYGTSGGLPRAKRKSVRTIAVVLAVFALCFLPFHVTRTLYYSFRSLDLSCHTLNAINMAYKVTRPLASANSCLDPVLYFLAGQRLVRFARDAKPPTGPSPATPARRRLGLRRSDRTDMQRIEDVLGSSEDSRRTESTPAGSENTKDIRL
  
Inhibitor
Name:
BDBM18137
Synonyms:
adenosine 5 -monophosphate | CHEMBL752 | [(2R,3S,4R,5R)-5-adenin-9-yl-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl dihydrogen phosphate;hydrate | {[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}phosphonic acid | AMP | US11185100, TABLE 7.3
Type:
Nucleoside or nucleotide
Emp. Form.:
C10H14N5O7P
Mol. Mass.:
347.06
SMILES:
c1nc(c2c(n1)n(cn2)[C@H]3[C@@H]([C@@H]([C@H](O3)COP(=O)(O)O)O)O)N
Structure:
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