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Target
D(4) dopamine receptor
Ligand
BDBM50119381
Substrate
n/a
Meas. Tech.
ChEMBL_60668 (CHEMBL671704)
Ki
68±n/a nM
Citation
 Bettinetti, L; Schlotter, K; Hübner, H; Gmeiner, P Interactive SAR studies: rational discovery of super-potent and highly selective dopamine D3 receptor antagonists and partial agonists. J Med Chem 45:4594-7 (2002) [PubMed]  Article 
Target
Name:
D(4) dopamine receptor
Synonyms:
D(2C) dopamine receptor | DOPAMINE D4 | DOPAMINE D4.2 | DOPAMINE D4.4 | DRD4 | DRD4_HUMAN | Dopamine D4 receptor
Type:
Enzyme
Mol. Mass.:
48373.19
Organism:
Homo sapiens (Human)
Description:
P21917
Residue:
419
Sequence:
MGNRSTADADGLLAGRGPAAGASAGASAGLAGQGAAALVGGVLLIGAVLAGNSLVCVSVATERALQTPTNSFIVSLAAADLLLALLVLPLFVYSEVQGGAWLLSPRLCDALMAMDVMLCTASIFNLCAISVDRFVAVAVPLRYNRQGGSRRQLLLIGATWLLSAAVAAPVLCGLNDVRGRDPAVCRLEDRDYVVYSSVCSFFLPCPLMLLLYWATFRGLQRWEVARRAKLHGRAPRRPSGPGPPSPTPPAPRLPQDPCGPDCAPPAPGLPRGPCGPDCAPAAPSLPQDPCGPDCAPPAPGLPPDPCGSNCAPPDAVRAAALPPQTPPQTRRRRRAKITGRERKAMRVLPVVVGAFLLCWTPFFVVHITQALCPACSVPPRLVSAVTWLGYVNSALNPVIYTVFNAEFRNVFRKALRACC
  
Inhibitor
Name:
BDBM50119381
Synonyms:
CHEMBL139600 | N-(5-(4-(2-methoxyphenyl)piperazin-1-yl)pentyl)H-pyrazolo[1,5-a]pyridine-3-carboxamide | Pyrazolo[1,5-a]pyridine-3-carboxylic acid {5-[4-(2-methoxy-phenyl)-piperazin-1-yl]-pentyl}-amide
Type:
Small organic molecule
Emp. Form.:
C24H31N5O2
Mol. Mass.:
421.5352
SMILES:
COc1ccccc1N1CCN(CCCCCNC(=O)c2cnn3ccccc23)CC1
Structure:
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