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Target
Mu-type opioid receptor
Ligand
BDBM50121645
Substrate
n/a
Meas. Tech.
ChEMBL_70854 (CHEMBL680354)
IC50
6.360±n/a nM
Citation
 Balboni, G; Salvadori, S; Guerrini, R; Negri, L; Giannini, E; Jinsmaa, Y; Bryant, SD; Lazarus, LH Potent delta-opioid receptor agonists containing the Dmt-Tic pharmacophore. J Med Chem 45:5556-63 (2002) [PubMed]  Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOR-1 | Mu opioid receptor | Mu-type opioid receptor (Mu) | OPIATE Mu | OPRM1 | OPRM_CAVPO
Type:
Enzyme Catalytic Domain
Mol. Mass.:
11165.58
Organism:
GUINEA PIG
Description:
P97266
Residue:
98
Sequence:
YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI
  
Inhibitor
Name:
BDBM50121645
Synonyms:
2-[(2S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl]-N-[(1S)-1-(1H-1,3-benzodiazol-2-yl)ethyl]-1,2,3,4-tetrahydroisoquinoline-3-carboxamide | 2-[2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-propionyl]-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid [1-(1H-benzoimidazol-2-yl)-ethyl]-amide
Type:
Small organic molecule
Emp. Form.:
C30H33N5O3
Mol. Mass.:
511.6147
SMILES:
C[C@H](NC(=O)C1Cc2ccccc2CN1C(=O)[C@@H](N)Cc1c(C)cc(O)cc1C)c1nc2ccccc2[nH]1
Structure:
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