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Target
P-selectin glycoprotein ligand 1
Ligand
BDBM50111451
Substrate
n/a
Meas. Tech.
ChEMBL_148143 (CHEMBL755250)
IC50
2500000±n/a nM
Citation
 Kaila, N; Chen, L; Thomas, BE; Tsao, D; Tam, S; Bedard, PW; Camphausen, RT; Alvarez, JC; Ullas, G Beta-C-mannosides as selectin inhibitors. J Med Chem 45:1563-6 (2002) [PubMed]  Article 
Target
Name:
P-selectin glycoprotein ligand 1
Synonyms:
P-selectin glycoprotein ligand 1 | P-selectin/P-selectin glycoprotein ligand 1 | SELPLG | SELPL_HUMAN
Type:
PROTEIN
Mol. Mass.:
43174.76
Organism:
Homo sapiens (Human)
Description:
ChEMBL_649756
Residue:
412
Sequence:
MPLQLLLLLILLGPGNSLQLWDTWADEAEKALGPLLARDRRQATEYEYLDYDFLPETEPPEMLRNSTDTTPLTGPGTPESTTVEPAARRSTGLDAGGAVTELTTELANMGNLSTDSAAMEIQTTQPAATEAQTTQPVPTEAQTTPLAATEAQTTRLTATEAQTTPLAATEAQTTPPAATEAQTTQPTGLEAQTTAPAAMEAQTTAPAAMEAQTTPPAAMEAQTTQTTAMEAQTTAPEATEAQTTQPTATEAQTTPLAAMEALSTEPSATEALSMEPTTKRGLFIPFSVSSVTHKGIPMAASNLSVNYPVGAPDHISVKQCLLAILILALVATIFFVCTVVLAVRLSRKGHMYPVRNYSPTEMVCISSLLPDGGEGPSATANGGLSKAKSPGLTPEPREDREGDDLTLHSFLP
  
Inhibitor
Name:
BDBM50111451
Synonyms:
2-[2-(3,4,5-Trihydroxy-6-{[2-(1-phenyl-ethylcarbamoyl)-benzoylamino]-methyl}-tetrahydro-pyran-2-yl)-acetylamino]-pentanedioic acid | CHEMBL288811
Type:
Small organic molecule
Emp. Form.:
C29H35N3O11
Mol. Mass.:
601.6017
SMILES:
C[C@@H](NC(=O)c1ccccc1C(=O)NCC1OC(CC(=O)N[C@@H](CCC(O)=O)C(O)=O)C(O)C(O)C1O)c1ccccc1
Structure:
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