Reaction Details Report a problem with these data
Target
Hydroxycarboxylic acid receptor 2
Ligand
BDBM50132140
Substrate
n/a
Meas. Tech.
ChEMBL_144336 (CHEMBL751847)
Ki
156±n/a nM
Citation
 van Herk, T; Brussee, J; van den Nieuwendijk, AM; van der Klein, PA; IJzerman, AP; Stannek, C; Burmeister, A; Lorenzen, A Pyrazole derivatives as partial agonists for the nicotinic acid receptor. J Med Chem 46:3945-51 (2003) [PubMed]  Article 
Target
Name:
Hydroxycarboxylic acid receptor 2
Synonyms:
Gpr109 | Gpr109a | Gpr109b | HCAR2_RAT | HM74 nicotinic acid GPCR | Hcar2 | Niacr1 | Pumag
Type:
PROTEIN
Mol. Mass.:
41476.06
Organism:
Rattus norvegicus
Description:
ChEMBL_820675
Residue:
360
Sequence:
MSKQNHFLVINGKNCCVFRDENIAKVLPPVLGLEFVFGLLGNGLALWIFCFHLKSWKSSRIFLFNLAVADFLLIICLPFLTDNYVQNWDWRFGSIPCRVMLFMLAMNRQGSIIFLTVVAVDRYFRVVHPHHFLNKISNRTAAIISCFLWGITIGLTVHLLYTDMMTRNGDANLCSSFSICYTFRWHDAMFLLEFFLPLGIILFCSGRIIWSLRQRQMDRHVKIKRAINFIMVVAIVFVICFLPSVAVRIRIFWLLYKHNVRNCDIYSSVDLAFFTTLSFTYMNSMLDPVVYYFSSPSFPNFFSTCINRCLRRKTLGEPDNNRSTSVELTGDPSTIRSIPGALMTDPSEPGSPPYLASTSR
  
Inhibitor
Name:
BDBM50132140
Synonyms:
1,4,5,6-Tetrahydro-cyclopentapyrazole-3-carboxylic acid | 1,4,5,6-Tetrahydrocyclopenta[c]pyrazole-3-carboxylic Acid | 2,4,5,6-tetrahydrocyclopenta[c]pyrazole-3-carboxylate | 2,4,5,6-tetrahydrocyclopenta[c]pyrazole-3-carboxylic acid | CHEMBL128604
Type:
Small organic molecule
Emp. Form.:
C7H8N2O2
Mol. Mass.:
152.1506
SMILES:
OC(=O)c1n[nH]c2CCCc12
Structure:
Search PDB for entries with ligand similarity: