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Target
Solute carrier family 15 member 1
Ligand
BDBM50137021
Substrate
n/a
Meas. Tech.
ChEMBL_89213 (CHEMBL699705)
Ki
100000±n/a nM
Citation
 Gebauer, S; Knütter, I; Hartrodt, B; Brandsch, M; Neubert, K; Thondorf, I Three-dimensional quantitative structure-activity relationship analyses of peptide substrates of the mammalian H+/peptide cotransporter PEPT1. J Med Chem 46:5725-34 (2003) [PubMed]  Article 
Target
Name:
Solute carrier family 15 member 1
Synonyms:
Intestinal H(+)/peptide cotransporter | Oligopeptide transporter small intestine isoform | Oligopeptide transporter, small intestine isoform | PEPT1 | Peptide transporter 1 | S15A1_HUMAN | SLC15A1
Type:
PROTEIN
Mol. Mass.:
78818.07
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1488839
Residue:
708
Sequence:
MGMSKSHSFFGYPLSIFFIVVNEFCERFSYYGMRAILILYFTNFISWDDNLSTAIYHTFVALCYLTPILGALIADSWLGKFKTIVSLSIVYTIGQAVTSVSSINDLTDHNHDGTPDSLPVHVVLSLIGLALIALGTGGIKPCVSAFGGDQFEEGQEKQRNRFFSIFYLAINAGSLLSTIITPMLRVQQCGIHSKQACYPLAFGVPAALMAVALIVFVLGSGMYKKFKPQGNIMGKVAKCIGFAIKNRFRHRSKAFPKREHWLDWAKEKYDERLISQIKMVTRVMFLYIPLPMFWALFDQQGSRWTLQATTMSGKIGALEIQPDQMQTVNAILIVIMVPIFDAVLYPLIAKCGFNFTSLKKMAVGMVLASMAFVVAAIVQVEIDKTLPVFPKGNEVQIKVLNIGNNTMNISLPGEMVTLGPMSQTNAFMTFDVNKLTRINISSPGSPVTAVTDDFKQGQRHTLLVWAPNHYQVVKDGLNQKPEKGENGIRFVNTFNELITITMSGKVYANISSYNASTYQFFPSGIKGFTISSTEIPPQCQPNFNTFYLEFGSAYTYIVQRKNDSCPEVKVFEDISANTVNMALQIPQYFLLTCGEVVFSVTGLEFSYSQAPSNMKSVLQAGWLLTVAVGNIIVLIVAGAGQFSKQWAEYILFAALLLVVCVIFAIMARFYTYINPAEIEAQFDEDEKKNRLEKSNPYFMSGANSQKQM
  
Inhibitor
Name:
BDBM50137021
Synonyms:
2-[(2-ammonio-3-methylbutanoyl)amino]-3-(4-hydroxyphenyl)propanoate | CHEMBL152586
Type:
Small organic molecule
Emp. Form.:
C14H20N2O4
Mol. Mass.:
280.3196
SMILES:
CC(C)C([NH3+])C(=O)NC(Cc1ccc(O)cc1)C([O-])=O
Structure:
Search PDB for entries with ligand similarity: