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Target
Thymidine kinase, cytosolic
Ligand
BDBM1
Substrate
n/a
Meas. Tech.
ChEMBL_208002 (CHEMBL816084)
Ki
200±n/a nM
Citation
 Russ, P; Schelling, P; Scapozza, L; Folkers, G; Clercq, ED; Marquez, VE Synthesis and biological evaluation of 5-substituted derivatives of the potent antiherpes agent (north)-methanocarbathymine. J Med Chem 46:5045-54 (2003) [PubMed]  Article 
Target
Name:
Thymidine kinase, cytosolic
Synonyms:
KITH_HUMAN | TK1
Type:
PROTEIN
Mol. Mass.:
25476.50
Organism:
Human
Description:
ChEMBL_1333884
Residue:
234
Sequence:
MSCINLPTVLPGSPSKTRGQIQVILGPMFSGKSTELMRRVRRFQIAQYKCLVIKYAKDTRYSSSFCTHDRNTMEALPACLLRDVAQEALGVAVIGIDEGQFFPDIVEFCEAMANAGKTVIVAALDGTFQRKPFGAILNLVPLAESVVKLTAVCMECFREAAYTKRLGTEKEVEVIGGADKYHSVCRLCYFKKASGQPAGPDNKENCPVPGKPGEAVAARKLFAPQQILQCSPAN
  
Inhibitor
Name:
BDBM1
Synonyms:
dT | thymidine
Type:
Nucleoside or nucleotide
Emp. Form.:
C10H14N2O5
Mol. Mass.:
242.2286
SMILES:
Cc1cn([C@H]2C[C@H](O)[C@@H](CO)O2)c(=O)[nH]c1=O
Structure:
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