Reaction Details Report a problem with these data
Target
Vasopressin V2 receptor
Ligand
BDBM50370400
Substrate
n/a
Meas. Tech.
ChEMBL_215012 (CHEMBL818810)
IC50
380±n/a nM
Citation
 Itzhak, Y; Kalir, A; Weissman, BA; Cohen, S New analgesic drugs derived from phencyclidine. J Med Chem 24:496-9 (1981) [PubMed]  Article 
Target
Name:
Vasopressin V2 receptor
Synonyms:
AVPR V2 | Antidiuretic hormone receptor | Avpr2 | Renal-type arginine vasopressin receptor | V2R_RAT | VASOPRESSIN V2 | Vasopressin receptor
Type:
G-protein coupled receptor
Mol. Mass.:
40761.85
Organism:
Rattus norvegicus (Rat)
Description:
n/a
Residue:
371
Sequence:
MLLVSTVSAVPGLFSPPSSPSNSSQEELLDDRDPLLVRAELALLSTIFVAVALSNGLVLGALIRRGRRGRWAPMHVFISHLCLADLAVALFQVLPQLAWDATDRFHGPDALCRAVKYLQMVGMYASSYMILAMTLDRHRAICRPMLAYRHGGGARWNRPVLVAWAFSLLLSLPQLFIFAQRDVGNGSGVFDCWARFAEPWGLRAYVTWIALMVFVAPALGIAACQVLIFREIHASLVPGPSERAGRRRRGRRTGSPSEGAHVSAAMAKTVRMTLVIVIVYVLCWAPFFLVQLWAAWDPEAPLERPPFVLLMLLASLNSCTNPWIYASFSSSVSSELRSLLCCAQRHTTHSLGPQDESCATASSSLMKDTPS
  
Inhibitor
Name:
BDBM50370400
Synonyms:
CHEMBL176264
Type:
Small organic molecule
Emp. Form.:
C29H27N3O2
Mol. Mass.:
449.5436
SMILES:
Cn1ccc2N(CCCCc12)C(=O)c1ccc(NC(=O)c2ccccc2-c2ccccc2)cc1
Structure:
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